Osteopathic Medicine and Primary Care
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ReviewIdentification of the patient with enlarged prostate: diagnosis and guidelines for managementSteven A Kaplan  Professor of Urology and Chief, Institute for Bladder and Prostate Health, Weill Medical College of Cornell University, F9 – West, Box 261, 1300 York Avenue, New York, NY 10021, USA author email corresponding author email
Osteopathic Medicine and Primary Care 2007,
1:11doi:10.1186/1750-4732-1-11 Abstract
Benign enlargement of the prostate, also referred to as benign prostatic hyperplasia, is a common condition in men. Because enlarged prostate (EP) was viewed historically as a symptomatic condition, management of voiding symptoms with α-blockers was often the goal of therapy. However, it is now recognized that EP is a progressive disorder, which may be complicated by acute urinary retention and which may eventually require EP-related surgery. The 5α-reductase inhibitors decrease dihydrotestosterone levels, which slow disease progression by causing regression of the prostate epithelial cells. These agents are considered disease modifying, and they may reduce the progression of prostate enlargement. This article reviews evaluation, diagnosis, and treatment strategies for EP, and it provides a practical algorithm for management of patients with EP. |