Osteopathic Medicine and Primary Care
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 ReviewManagement of progressive type 2 diabetes: role of insulin therapyRamachandra Rahul V Chemitiganti  and Craig W Spellman  Texas Tech University Health Science Center, 701 West 5th Street, Odessa, TX 79763, USA  author email corresponding author email
Osteopathic Medicine and Primary Care 2009,
3:5doi:10.1186/1750-4732-3-5 Abstract
Insulin is an effective treatment for achieving tight glycemic control and improving clinical outcomes in patients with diabetes. While insulin therapy is required from the onset of diagnosis in type 1 disease, its role in type 2 diabetes requires consideration as to when to initiate and advance therapy. In this article, we review a case study that unfolds over 5 years and discuss the therapeutic decision points, initiation and advancement of insulin regimens, and analyze new data regarding the advantages and disadvantages of tight management of glucose levels. | 
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