Osteopathic Medicine and Primary Care


Open Access Review

Management of progressive type 2 diabetes: role of insulin therapy

Ramachandra RV Chemitiganti and Craig W Spellman*

Author Affiliations

Texas Tech University Health Science Center, 701 West 5th Street, Odessa, TX 79763, USA

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Osteopathic Medicine and Primary Care 2009, 3:5 doi:10.1186/1750-4732-3-5

Published: 2 July 2009

Abstract

Insulin is an effective treatment for achieving tight glycemic control and improving clinical outcomes in patients with diabetes. While insulin therapy is required from the onset of diagnosis in type 1 disease, its role in type 2 diabetes requires consideration as to when to initiate and advance therapy. In this article, we review a case study that unfolds over 5 years and discuss the therapeutic decision points, initiation and advancement of insulin regimens, and analyze new data regarding the advantages and disadvantages of tight management of glucose levels.